This is information I compiled related to questions concerning Thyroglobulin Antibodies (TgAb) remaining elevated or increasing following total thyroidectomy despite having low or undetectable Thyroglobulin (Tg) and whether TgAb can be used to detect recurrence of thyroid cancer.
Serum Thyroglobulin (Tg) is the primary tumor marker measured postoperatively to monitor for recurrence of thyroid cancer. Tg concentrations reflect the mass, or amount, of residual thyroid tissue — remnant or tumor. An unexpected elevated Tg result which is not consistent with clinical findings and history is distressing for the patient and can lead to… Continue reading Falsely Elevated Thyroglobulin – HAMA
Thyroglobulin Testing When You Have Positive Antibodies (TgAb} Thyroglobulin (Tg) is produced only by thyroid tissue and is the primary marker for follow up thyroid cancer detection after total thyroidectomy. It is not generally used after a partial or hemi-thyroidectomy as the remaining thyroid lobe will still produce normal levels of thyroglobulin. If you have thyroglobulin… Continue reading Tg Testing with Antibodies